Patient Reported Outcomes (Child Health Questionnaire & Infant Toddler Quality of Life Questionnaire)
HACHQ has developed and licensed Patient Reported Outcomes surveys over the last twenty years. The principal surveys from our observer-reported (ObsRO) toolkit portfolio include the CHQ (Child Health Questionnaire and the ITQOL (Infant Toddler Quality of Life) - legacy surveys focused on pediatric and adolescent health-related quality of life (HRQOL). These comprehensive measures assess the child / adolescent / infants physical, emotional and social well-being from the parent’s perspective and also capture the overall well-being of the parent and family. As recommended by the FDA, EMA, NICE and others, the CHQ is also available as a child / adolescent self-report PRO measure.
The CHQ and ITQOL PRO measures are made available for limited use licensure by all researchers - including academic researchers, pharmaceutical firms, clinical care providers, and governmental and organizational investigators. Licenses have been approved and granted to thousands of researchers and companies to document the health and well-being of the pediatric / adolescent population and to measure changes in health over time. The Company also develops and licenses condition-specific surveys to dimension the functional outcomes and impacts of defined health conditions.
Patient Reported Outcomes Survey Development
A rigorous multi-staged approach is the focus of developing new and existing surveys. This comprehensive process includes direct input from adult and child patients and their families - as well as from clinical and academic experts through a qualitative interview process.
HealthActCHQ's Approach to PRO's: Constructing and Scoring Health-Related Quality of Life (HRQOL) & Observer Reported Outcomes (ObsRO) Surveys
HACHQ employs the Likert method of summated ratings to design all of our surveys. This method is preferred because it is based on scaling assumptions that can be empirically tested and allows for simplicity in scoring and interpreting findings. The summative approach is the hallmark method used in the construction and evaluation of widely accepted quality of life measures for both adults and children.
- Graduated response continuums such as "a lot" to "not at all" and "very satisfied" to "very dissatisfied" are used.
- Scale scores are computed by deriving the algebraic mean of each scale and transforming the raw score on a 0-to-100 continuum.
- Using standard scoring conventions, a higher score is always more favorable.
- HACHQ scoring eManuals are available exclusively for licensed users.
HealthActCHQ's eManuals for Scoring Patient Reported Outcomes Surveys: An Important Note
With the use of all PRO Surveys, familiarity with clinical and scientific research skills and methods are recommended. Scoring the scales – the sets of items – in each of the HACHQ surveys requires basic programming skills and a familiarity with SPSS, SAS, STATA, EXCEL, or an equivalent statistical database and analytic software program. HealthActCHQ's proprietary scoring algorithms are provided to each licensed user in our User eManuals to guide you in creating the code for calculating individual scale score means – profiles - for each survey, as well as the component summary scores when warranted as with the Child Health Questionnaire parent-reported surveys.
Due to intellectual property considerations, surveys are not made available for review prior to completion of a License Agreement and the payment of fees. The survey content is presented at this website for review and has been effectively used for both IRB and Ethics submissions. Survey information may be downloaded in pdf format for regulatory submissions.